Metabolic Characterization of a Rare Genetic Variation Within APOC3 and Its Lipoprotein Lipase–Independent Effects

This paper characterizes the effects of the rare APOC3 loss of function mutation on lipid metabolism in two large European population cohorts.

The results improve understanding of the role of APOC3 in triglyceride metabolism, its LPL independent action and elucidates the suitable as a new lipid-lowering target.

Stay in the know

Our latest health headlines delivered to your inbox.