January 23, 2018

Circulating Metabolic Biomarkers of Screen-Detected Prostate Cancer in the ProtecT

Adams et al. Cancer Epidemiol Biomarkers Prevention 2019;28(1):208-16

Researchers identified 35 circulating metabolites associated with prostate cancer presence, but found no evidence of causality for those 14 testable with MR.

Thus, the 14 MR-tested metabolites are unlikely to be mechanistically important in prostate cancer risk. Impact: The metabolome provides a promising set of biomarkers that may aid prostate cancer classification.