Human genetics
June 1, 2017

CPT1A Missense Mutation Associated With Fatty Acid Metabolism and Reduced Height in Greenlanders

Skotte et al. Circulation: Cardiovascular Genetics 2017;10(3):e001618

This paper investigates the association between long‐term weight change and blood metabolites.

Thirty metabolites were significantly associated with change in BMI per year in TwinsUK using Bonferroni correction. Metabolites linked to higher oxidative stress were concluded to associate with increased long‐term weight gain.