Human genetics
November 15, 2016

Genetic predisposition to an impaired metabolism of the branched-chain amino acids and risk of type 2 diabetes: A Mendelian randomisation analysis

Lotta et al. PLoS Medicine 2016;13(11):e1002179

Evidence from this large-scale human genetic and metabolomic study suggests a causal role of branched-chain amino acids metabolism in the etiology of type 2 diabetes.