September 3, 2017

Genome metabolome integrated network analysis to uncover connections between genetic variants and complex traits: an application to obesity

Valcárcel et al. Journal of the Royal Society Interface 2014;11(94):20130908

In this paper, a novel methodology is proposed.

Referred to as genome metabolome integrated network analysis (GEMINi), the approach combines network analysis with genome-wide correlations to exploit differences in molecular associations to uncover genetic variants.