Genome metabolome integrated network analysis to uncover connections between genetic variants and complex traits: an application to obesity
Valcárcel et al. Journal of the Royal Society Interface 2014;11(94):20130908
In this paper, a novel methodology is proposed.
Referred to as genome metabolome integrated network analysis (GEMINi), the approach combines network analysis with genome-wide correlations to exploit differences in molecular associations to uncover genetic variants.