Human genetics
April 2, 2012

Genome-wide association study identifies multiple loci influencing human serum metabolite levels

Kettunen et al. Nature Genetics 2012;44(3):269-76

This paper, based on n≈8300 individuals, uncovers numerous genes not previously known to regulate human metabolism.

Using twin data, the study further establishes the heritability of 115 metabolite concentrations and 99 ratios.