Maternal depression and inflammation during pregnancy

This paper examined the relationship between depression and inflammatory state during pregnancy by analyzing plasma high-sensitivity C-reactive protein (hsCRP) and glycoprotein acetyls (GlycA) at three consecutive stages during pregnancy.

Depression was associated with a proinflammatory state during pregnancy. These associations were shown to be mediated by early pregnancy BMI. In addition, depressive symptoms during pregnancy aggravated the inflammation related to obesity.