Ellul et al. BMJ Open 2019 Jul 4;9(Suppl 3):106-117
In this paper, researchers examined the circulating metabolic profiles of a sample of Australian 11-12 year olds children and their parents, described differences by age and sex and explored the correlation of metabolites in parent-child dyads.
In general, metabolite concentrations were higher in adults than children and sex differences were larger in adults than in children. Positive correlations were observed for the majority of metabolites including isoleucine, total cholesterol and omega 6 fatty acids in parent-child comparisons. These data will be informative for investigation of the childhood origins of adult non-communicable diseases and for comparative studies in other populations.