Gut microbiota
September 23, 2018

Six-Week Endurance Exercise Alters Gut Metagenome That Is not Reflected in Systemic Metabolism in Over-weight Women

Munukka et al. Front Microbiol. 2018;9:2323

Researchers determined whether six-weeks endurance exercise, without changing diet, affected the gut metagenome and systemic metabolites of overweight women.

Previously sedentary overweight women underwent a six-weeks endurance exercise intervention. The gut microbiota composition and functions were analyzed by 16S rRNA gene amplicon sequencing and metagenomics. Body composition was analyzed with DXA X-ray densitometer and serum metabolomics with Nightingale's NMR metabolomics. As a results, exercise training modified the gut microbiome without greatly affecting systemic metabolites or body composition.