Cardiovascular diseases
August 22, 2016

Variant rs10911021 that associates with coronary heart disease in type 2 diabetes, is associated with lower concentrations of circulating HDL cholesterol and large HDL particles but not with amino acids

Beaney et al. Cardiovascular Diabetology 2016;15(1):115

The findings of this study verify the association between rs10911021 and coronary heart disease in patients with type 2 diabetes.

While the genetic variant did not associate with glutamine and other quantified amino acids, there was an effect on several HDL particle traits specifically for diabetic patients.