CSF Biomarker Analysis

Nightingale’s cerebrospinal metabolic biomarkers provide the opportunity to elucidate molecular mechanisms.

An emerging platform

We provide simultaneous quantification of metabolites from different metabolic pathways, including energy metabolism, fluid balance and carbohydrates. The nearly 30 metabolites are analysed from a single measurement of 150µL or 500µL of human cerebrospinal fluid and are provided in molar concentration units.

An emerging platform

We provide simultaneous quantification of metabolites from different metabolic pathways, including energy metabolism, fluid balance and carbohydrates. The nearly 30 metabolites are analysed from a single measurement of 150µL or 500µL of human cerebrospinal fluid and are provided in molar concentration units.

Exploring changes in the central nervous system

Metabolic biomarker analysis of cerebrospinal fluid (CSF) samples provides an opportunity to examine the molecular mechanisms of neurodegenerative diseases, such as dementia, Parkinson’s Disease and Multiple Sclerosis. One of the key application areas for CSF analysis is biomarker discovery for disease onset and prognosis.

Exploring changes in the central nervous system

Metabolic biomarker analysis of cerebrospinal fluid (CSF) samples provides an opportunity to examine the molecular mechanisms of neurodegenerative diseases, such as dementia, Parkinson’s Disease and Multiple Sclerosis. One of the key application areas for CSF analysis is biomarker discovery for disease onset and prognosis.

Complementing methods

As metabolites reflect the interplay of genetic and environmental factors, some of them are able to cross the blood-brain barrier and be modifiable through dietary or pharmacological interventions. By combining Nightingale’s metabolic biomarker analyses from cerebrospinal fluid and blood, it’s possible to uncover novel molecular insights that influence neurodegenerative diseases, for example understand how the subtle leakage of the blood-brain barrier influences the development of these diseases.

Complementing methods

As metabolites reflect the interplay of genetic and environmental factors, some of them are able to cross the blood-brain barrier and be modifiable through dietary or pharmacological interventions. By combining Nightingale’s metabolic biomarker analyses from cerebrospinal fluid and blood, it’s possible to uncover novel molecular insights that influence neurodegenerative diseases, for example understand how the subtle leakage of the blood-brain barrier influences the development of these diseases.

Founded on scientific excellence

Nightingale's analysis services are built on our award-winning technology that has been used in over 200 peer-reviewed scientific papers. It is continuously employed to advance research related to chronic disease prevention. 

Our technology

Founded on scientific excellence

Nightingale's analysis services are built on our award-winning technology that has been used in over 200 peer-reviewed scientific papers. It is continuously employed to advance research related to chronic disease prevention. 

Our technology

Our service

Producing high quality data and ensuring you get the most out of your research is a core part of our service.

Reproducible measurements

Our data is concordant with routine chemistry analyses. There are no batch-effects ensuring robust data quality.

Ready-to-use results

Our data reports provide you with fully quantified biomarker results in absolute concentration units.

Integrated quality control

Together with your results data, you also get a detailed description of the quality of your samples to support the strength of your methodology.

In-house expertise

Our in-house science team is happy to support you from study design and data analysis, to results interpretation.


Working together with us

Our service process is simple, and we are ready to work with you at any time. We're happy to hear from you whether you are in the planning stage of your study, or whether you're ready to ship your samples.

Collaboration call

Sending samples

Sample analysis

Results delivery & consultative call

Returning remaining sample material


Pricing

Our high-throughput metabolomics technology allows for analyzing samples at a very competitive price for any size of sample sets. Pricing is based on sample number and sample volume: the more samples you have, the lower the price per sample is.  

For example, a project with samples in the hundreds typically would cost 100-125€ per sample, while a set of few thousand samples would cost 80-100€ per sample. To get an exact price for your samples, please contact us for a quote below. 

 

Our high-throughput metabolomics technology allows for analyzing samples at a very competitive price for any size of sample sets. Pricing is based on sample number and sample volume: the more samples you have, the lower the price per sample is.  

For example, a project with samples in the hundreds typically would cost 100-125€ per sample, while a set of few thousand samples would cost 80-100€ per sample. To get an exact price for your samples, please contact us for a quote below. 

 

Contact

Whether you have a question or you would like to ask for an offer, let us know and we'll get back to you very soon.

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