Urine sample collection

Urine Q&A

Urine sample collection

Sample collection

What volume is needed for urine sample analysis?

Our urine analysis technology requires a minimum of 500 µL of liquid urine. As there may be some precipitate in urine, please make sure to send at least 550 µL of liquid urine, if available.

How should the samples be collected?

For sample collection, we recommend following international guidelines and standards.

Do you prefer morning urine, spot urine or 24-hour urine?

This very much depends on the study setting and what you are interested in. Random spot urine is the most uncertain and therefore, some biomarkers might not be available due to their lower concentration, as water content may be higher in spot urine samples than in morning urine samples. We recommend morning urine, as biologically, it is the most valuable. However, also 24-hour urine is perfectly fine.

How should the samples be processed after collection/ arrival in our lab?

As there may be sometimes solid precipitate in urine, we recommend centrifuging the urine to remove the precipitate before aliquoting and storing the urine samples. No further processing is required. The aliquoted samples should be stored at -80°C as soon as possible.

Can you analyse samples, which contain additives or whose pH has been adjusted?

We do not currently have insight on the effect of pH adjustment before storage on biomarker results, nor have we carried out any extensive research on this. Should you have the choice, do send samples without any preservatives or processing. However, we have no reason to believe that samples whose pH has been adjusted would be beyond analysis. When it comes to additives, samples with some of the most commonly used additives like sodium azide and borate are also suitable for our urine analysis technology. If you are in doubt, please consult us for further information.