Nightingale’s biomarker analysis
New Standard in Blood Testing
Nightingale’s biomarker analysis platform is the world-leading solution for comprehensive metabolic profiling. With a single blood test, it offers over 220 metabolic biomarkers for chronic diseases with an unmatched price level.
Scalable by design
Nightingale’s biomarker analysis platform is designed from scratch to transform population medicine. It combines low-cost and high scalability by measuring a high number of biomarkers from a single blood sample. Compared to the current lipid tests, up to 50x more biomarkers are obtained with an unmatched price level. The technology scales to any number of samples, providing fast delivery times.
Over 220 biomarker measures
Nightingale’s biomarker analysis platform covers both routine lipid measures and a wealth of emerging predictive and diagnostic disease biomarkers. Amino acids, fatty acids, glycolysis metabolites, and lipoprotein subclasses are obtained simultaneously with routine clinical lipid measures. The biomarkers give unprecedented insight into human metabolism while also reflecting different aspects of health and disease.Overview of biomarkers
Accurate and automated technology
Nightingale’s analysis acquires the biomarker measurements using automated sample preparation, NMR (nuclear magnetic resonance) and sophisticated data analysis. The results are delivered in absolute concentrations (mmol/l) with Nightingale’s proprietary software.Scientific overview of Nightingale’s technology
This is how it's done
1. Serum or plasma samples
Nightingale’s analysis can acquire the biomarker measurements from any native serum or plasma which have been collected and kept according to standard procedures for lipid testing. Sample volumes of either 100 μl or 350 μl can be profiled for the same set of biomarkers for each sample.
2. Sample preparation
Minimal sample processing is performed by transferring serum or plasma samples into NMR measurement tubes and mixing solvent to them. The blood sample is never in direct contact with the NMR detector. This results in cost-effectiveness and unrivaled stability and robust biomarker quantification with no batch effects.
Proven by world-class science
Science is the foundation of our blood analysis technology. With over 400 000 blood samples analysed, and results published in over 100 scientific publications, the quality and value of our technology has been openly evaluated and demonstrated.See key publications