A blood sample is taken at home or lab

Nightingale Health’s technology requires only one blood sample.

Our technology can utilize venous blood samples collected as a part of routine healthcare or finger prick samples collected at home.

Venous samples do not require any special processing and can be sent to us using existing laboratory logistics. Since a very low amount of blood is needed, a sample taken for other purposes can be split and part of it forwarded for our analysis, minimizing the burden for patients.

Finger prick samples can be provided to us utilizing a self-collection device included in our home-kit. The self-collection device collects a standardized amount of blood. The device automatically separates the plasma from the collected blood and stores it as a dried sample, allowing the sample to be sent back to our laboratory via regular mail.

Sample is analyzed with Nightingale Health’s proprietary technology

We analyze each sample with our proprietary blood testing technology globally available only from Nightingale Health. The technology is created completely in-house and utilizes nuclear magnetic resonance spectroscopy (NMR).

The fully automated process begins with an NMR measurement that creates spectral data of the sample. Our proprietary purpose build algorithms and software processes the spectral data into concentrations of readable molecules in the case of venous samples (millimoles per litre or “mmol/L”) or, in the case of finger prick samples, into molecular input data for the calculation of Nightingale Health’s next-generation health metrics. Together, the full automation, extensive capture of molecular data, clinical laboratory level quality control, and high-throughput processing makes our technology revolutional.

Analysis reveals hundreds of molecules

Nightingale’s analysis produces up to 250 times more molecular health data than provided by a regular blood test, all from one sample. This health information provides a comprehensive picture of human metabolism. The same set of results analyzed with traditional methods would require several separate blood tests and samples.

We’ve already analyzed over a million samples and are analyzing samples with continuously increasing numbers. Our technology produces comprehensive, highly accurate, and repeatable biomarker results quickly and at a low cost on a mass scale. Nightingale Health operates under a certified quality management system in accordance with EN ISO 13485 and SFS-EN ISO/IEC 17025, and all blood samples are measured with a CE-marked IVD device. These factors have enabled Nightingale Health’s analysis to be brought to use in healthcare settings.

Our analysis measures biomarkers such as amino acids, apolipoproteins, cholesterols, fatty acids, fatty acid ratios, glycolysis metabolites, inflammation, ketone bodies, lipoprotein particle concentrations, lipoprotein particle sizes, lipoprotein subclasses, triglycerides, and more.

If you are interested in using our technology for medical research, visit our website for researchers here.

Risk prediction algorithms built based on hundreds of thousands of individuals

Once the molecular input data of a person’s metabolic profile has been created, we utilize our proprietary algorithms to go beyond biomarkers by providing a direct connection to disease risks and prediction of future health.

These algorithms utilize real-life data to directly link the measurement results to the risk of falling ill with the diseases that most commonly shorten active life. To date, we have analyzed hundreds of thousands of blood samples from international biobanks with our technology. Those analysis results have been compared using scientific data analyses to the medical records of the biobank participants. These analyses have found many diseases that are associated with the results of our blood test and form the basis for the calculation of our next-generation health metrics.